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Nucleus + Single-cell

Nucleus + Single-cell

Nucleus + Single-cell

Suspension Preparation Platform

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Nucleus + Single-cell

Suspension Preparation Platform

Singulator 100 single-cell (nucleus) suspension preparation system is a fully automated tissue dissociation system from S2 Genomics, enabling fast, automated and standardized dissociation of solid tissue into single-cell (nucleus) suspension. With this system, researchers can easily obtain highly active single-cell (nucleus) suspension. As such this system is suitable for use in genomics, cell biology and many other applications.

Nucleus + Single-cell

Capable of dissociating as little as 1mg of tissue samples of fragile cells such as protoplasts and nucleus

Capable of dissociating as little as 1mg of tissue samples of fragile cells such as protoplasts and nucleus

• Capable of dissociating samples ranging from 1 mg to 1000 mg .Suitable for human, mouse/rat/spiny rat, zebra fish, bee, Arabidopsis thaliana, etc. Compatible with most dissociation reagents

Nucleus and single cell dissociation with high yield

Nucleus and single cell dissociation with high yield

• 1,000-500,000/mg for single cell dissociation .Single cell viability is 85%-95% .2,000-600,000/mg for nucleus dissociation .Constant temperature at 6°C, room temperature and 37°C

"One-button" automatic dissociation

"One-button" automatic dissociation

• Multiple built-in dissociation protocols, "one-button" setting for input of tissue and output of cell/nucleus. Improved uniformity, repeatable results for similar samples in different laboratories, and reduced variability in cell transcript. Monitoring of dissociation process making it easy to track entire process

Fast dissociation

Fast dissociation

• 7-12 minutes for cell nucleus dissociation .20-30 minutes for dissociation of tissue into single-cell suspension

Capable of dissociating as little as 1mg of tissue samples of fragile cells such as protoplasts and nucleus Capable of dissociating as little as 1mg of tissue samples of fragile cells such as protoplasts and nucleus

Nucleus and single cell dissociation with high yield Nucleus and single cell dissociation with high yield

"One-button" automatic dissociation "One-button" automatic dissociation

Fast dissociation Fast dissociation

Nucleus + Single-cell

Nucleus + Single-cell

Application scenario

Single-cell RNA sequencing

Single-cell RNA sequencing

Single-nucleus RNA sequencing

Single-nucleus RNA sequencing

ATAC sequencing

ATAC sequencing

CITE sequencing

CITE sequencing

Flow cytometry

Flow cytometry

Primary cell culture

Primary cell culture

Basic tumor research

Basic tumor research

Technical Specifications

Product name Singulator Tissue Dissociation Suitable for Many Species and Tissue Types
Single-cell preparation Human: Colon tissue, colonic polyp, colon tumor, neck tumor, bladder, colorectal cancer
Mouse: Brain, kidney, liver, lung, spleen, ovary, colon (normal and PDX tissue)
Rat: Brain, kidney, lung, liver, spleen
Zebra fish: Brain, liver tissue
Turbellarian worm: Individual
Cell nucleus preparation Human: Brain (adult/infant/fetus), breast cancer, brain organoid, colon (normal tissue/polyp/tumor), heart (adult/fetus), hemangioma, small intestine (fetus), lung (fetus), muscle tissue (TA & SA), prostate (normal tissue and tumor), retinal organoid (wild and gene knockout), spleen (fetus), thymus (fetus), vascular anomaly (artery), vascular anomaly (lymphatic)
Mouse: Brain, colon (normal and PDX tissue), heart, intestines, kidney (normal and precystic tissues), liver, lung, lymph, muscle, pancreas PDX mouse tissue, spinal cord, spleen
Rat: Brain, kidney, liver, lung, spleen
Spiny rat: Kidney
Bee: Chest
Arabidopsis thaliana: Entire stalk, root tip

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