NGS
Fully Automated NGS Library Preparation System
BioHandler fully automated NGS library preparation system is specifically designed for NGS (Next-generation Sequencing) library preparation and/or target nucleic acid enrichment. The system has 20 standard bases and allows for 24-channel air displacement pipetting. By integrating various modules, such as thermal cycler, temperature control, magnetic stand, grasp and shaking module, it can support consumables required for library preparation of 48 DNA samples, eliminating the need for frequent manual replacement of consumables, thus enabling a truly unattended integrated pipetting workstation.
Precise and efficient
There are 20 standard bases, which can support consumables required for library preparation of 48 DNA samples without frequent manual replacement of consumables. 24-channel pipetting module enables rapid and precise liquid handling, effectively increasing run speed and avoiding experimental errors due to timing disparity.
Flexible configuration
The system is equipped with built-in programs for different library preparation kits. You can easily change modules on the deck and select different programs depending on your needs to run protocols for commercially available library preparation kits. For library preparation protocols with no hybridization capture steps, elevated magnetic stand configuration can be used to increase the number of tip plates and improve throughput. For library preparation + hybridization capture protocols, grasp and shaking module can be used to effectively improve hybridization capture.
Accurate and stable
The system is integrated with various modules to significantly reduce hands-on time, providing greater stability and reducing error rate. It also supports 24-hour continuous run time, and helps ensure high throughput, repetitiveness and precision in the NGS library preparation.
Easy operation
Built-in programs allow for one-click start, including library preparation, hybridization capture, normalization and pooling. It supports various combinations of functional modules, and is easy to installation, making it easy to meet your throughput, time and budget requirements in the NGS library preparation. Its open-concept design enables users to customize protocols according to their needs and generate applications, allowing automated operation with high level of flexibility. It also supports user-defined number of samples, and different programs can be selected based on the number of samples.
Safe and reliable
Integrated, fully automated sample preparation system helps reduce your hands-on effort. With its closed space, UV sterilization before and after running, and positive-pressure environment, it is capable of avoiding contamination caused by pathogens or bacteria, thereby ensuring personnel safety and high productivity.
Application scenario
Technical Specifications
Product name | Fully Automated NGS Library Preparation System |
Sample throughput* | DNA library preparation: ≤96 mRNA library preparation: ≤24 Multiplexed amplicon-based library preparation: ≤48 Probe-based hybridization capture and library preparation: ≤24 |
Sample type | DNA, RNA |
Deck capacity | 20 (4x5) |
Mechanical arm positioning precision | ±0.1mm |
Pipetting channel | 24-channel, compatible with 8 channels |
Volume range | 1μL-200μL |
Pipetting head | 50μL, 200μL |
Thermal cycler temperature | Temperature control: 0-105°C (≤±0.1°C) Heated lid: 30-110°C Temperature uniformity: ≤0.3°C @55°C |
Independent temperature control module | 2, 0-105℃ |
Magnetic stand module | 1, fixed or elevated |
Grasp module | 1, optional |
Shaking module/heated shaking module | Optional |
UV sterilization system | ≥100,000 μW.s/cm² |
Scanner | Supports bar code scanning |
Indicator lights | Four-red, orange, blue and green |
Dimensions (W×D×H) |
1100×704×916mm |
Weight | 155kg |
Power | AC100-240V, 50/60Hz, 1000W |
Operating environment | Operation ambient temperature: 10°C-40°C Relative humidity: 20%-80% |
Volume (μL) | Precision (≤CV%) | Accuracy (±%) | |
---|---|---|---|
1 | ≤5% | ±5% | |
20 | ≤2% | ±2% | |
100 | ≤1% | ±1% | |
200 | ≤1% | ±1% |
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